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tooot.im הוא שרת אחד משרתי מסטודון עצמאיים רבים שדרגם תוכלו להשתתף בפדיוורס (רשת חברתית מבוזרת).
Tooot.im, a Mastodon instance (He | En mostly) רשת מסטודון עברית | חופשית משיקולים תאגידיים | פדרטיבית עם הFediverse

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tooot.im: אודותספריית פרופיליםמדיניות פרטיות

Mastodon: אודותלהתקנת היישומוןקיצורי מקלדתצפיה בקוד המקורv4.3.6

#COVID19

110 הודעות85 משתתפיםות8 הודעות היום
פומבי
Augie Ray

STUDY of hospitalized (HS) and non-hospitalized (NHS) #COVID19 survivors after two years:

“78% of HS and 62% of NHS reported at least one sequela symptom. Sequelae-symptoms, neurological outcomes, restrictive spirometry findings, and electrocardiogram abnormalities remained unchanged, although psychiatric sequelae, quality of life, and exercise capacity improved in both groups. Two or more vaccine doses decreased the risk of respiratory and psychiatric sequelae.”

jogh.org/2025/jogh-15-04075

JOGH · Evolution of long COVID over two years in hospitalised and non-hospitalised survivors in Bangladesh: a longitudinal cohort study — JOGHPost-COVID syndrome, or long COVID, refers to the long-term health consequences of COVID-19 that can persist for months or even years after recovering from the acute infection [1,2]. Despite a significant decline in COVID-19 cases and the disease no longer being a global health emergency, new cases are still being reported. Between 4–31 March 2024, […]
פומבי
Augie Ray

"Omicron is milder."

STUDY of people infected with Omicron #COVID19 finds:

The odds of long COVID increased with reinfections: 2.592x higher for one reinfection and 6.171x higher for two or more.

7.8% experienced long COVID within one year, with 5.1% having persistent symptoms.

People w/ persistent long COVID had lower muscle strength, worse exercise capacity, poorer HRQoL, significantly higher proportions of abnormal lung function and lung imaging abnormalities.

thelancet.com/journals/lanwpc/

פומבי *
Augie Ray

I had to unfollow an account that I used to trust for #COVID19 info. It said the current level of COVID in wastewater is “unprecedented.”

COVID is bad enough without inflating risks. No one will listen to us when COVID risks are high if we say silly things like this when COVID is actually low (in aggregate) in the US.

I get it. COVID risks never disappear, but the accounts addicted to spreading fear rather than knowledge need to be rejected, IMO.

Chart of COVID in US wastewater, showing that COVID has been lower than current levels four times (around 50 weeks) in the past 35 months.
פומבי *
Ms. Opossum graphs COVID data.

UPDATED: #Quebec #SARSCoV2 variants.

⚠️ Only 50 & 20 samples for weeks of 2/23, 3/2 ⚠️

Of the 20,
XEC.*: 45% (⬆️ 18%; ⬇️ 29.8%)
LP.8.1.*: 20% (⬆️ 6%; ⬆️ 4.3%)
KP.3.1.1.*: 5% (⬇️ 22%; ⬇️ 23.4%)
LF.7.7.2: 25% (⬇️ 28%; ⬆️ 23.4%)

ratnegative.tumblr.com/QCVaria #COVID19

----------

Of the samples collected in Quebec on these weeks, the prevalence of significant variants/lineages are as follows:

- 3/2 - 3/8 - (20 samples; no threshold)
• XEC.* (incl. XEC.5, ".9, ".11): 45%
• JN.1.11.1.*: 25%
→ LP.8.1.*: (incl. LP.8.1.1): 20%
→ KP.3.* (only MC.10.1): 5%
• LF.7.* (incl. LF.7.7.2): 30%
→ LF.7.7.2: 25%

- 2/23 - 3/1 - (50 samples; 4% threshold)
• XEC.* (incl. XEC.2, ".9, ".13): 18%
• JN.1.11.1.*: 38%
→ LP.8.1.* (only LP.8.1.1): 6%
→ KP.3.* (only KP.3.1.*, ".3.3.5): 32%
→ KP.3.1.1.* (incl. MC.1.2, ".10.1.*, ".11, ".13.2.1, "28.1.1): 22%
→ MC.1.* (only MC.1.2): 10%
• LF.7.* (incl. LF.7.1, ".7.2.1, ".7.7.2): 40%
→ LF.7.7.2: 28%

X.X.* in text = X.X & descendants.
X.X.* in graph = all descendants of X.X, except for ones that have their own segment of the week’s bar. Please see "Notes on Usage" section.

שרשור מתמשך
פומבי
sport of sacred spherical cows

Second time #CDC has reported estimates for more than two regions at a time since October.

To be clear, national data used for chart above are modeled on regional data collection.

LP.8.1 now estimated at majority in Great Lakes, nearing majority in NY/NJ and Mid-Atlantic.

XEC (incl. XEC.4) still around a quarter share in all three regions.

[For color key, see: covid.cdc.gov/covid-data-track]

❖ #ThisIsOurPolio #Covid #Covid19 #SARS2 #variants #CovidIsNotOver #CovidIsAirborne #WearAMask #BetterMasks

Map: Nowcast Estimates for 3/2/2025 - 3/15/2025 by HHS Region Source: Centers for Disease Control Map shows pie charts for three of ten regions, reflecting regional estimated proportions for specimens collected for the most recent biweekly reporting period. Bold text over Canada portion of map reads: "Nowcast estimates are only available for HHS regions having at least 300 sequences in the two weeks ending 02/15/2025". Dominant strains by tracked region: NY/NJ: LP.8.1 (orange) 47%, XEC (clover) 22%, LF.7 (dirty blue) 5%, LB.1.3.1 (fountain blue) 5%. Mid-Atlantic: LP.8.1 (orange) 42%, XEC (clover) 25%, MC.28.1 (flat blue) 8%, KP.3.1.1 (sea bluish cyan) 5%. Great Lakes: LP.8.1 (orange) 60%, XEC (clover) 24%, KP.3.1.1 (sea bluish cyan) 4%. Of ten regions, seven regions are blank. ALT-text by beadsland at ko-fi.
שרשור מתמשך
פומבי
sport of sacred spherical cows

A FLuQE wavelet opened September, cresting as KP.3.1.1 / MC wave into November. FDA's second-guess vaccine target, KP.2, dropped out in December. Updated #CDC estimates indicate we've been in a JN.1.11 soup pretty much since then.

No new variants broken out by CDC, as KP.1.1.3 / LP descendant LP.8.1 approaches majority.

No recent GISAID data—as Raj's dashboard hasn't updated in near a month.

❖ #ThisIsOurPolio #Covid #Covid19 #SARS2 #variants #CovidIsNotOver #CovidIsAirborne #dataviz #datavis

Chart: Estimated U.S. Variant Proportions by Common Name Sources: Centers for Disease Control, CoV-Lineages, NYITCOM Research, Daniele Focosi, World Health Network, others [ beadsland on Ko-fi ] Reskin of CDC's Variants Nowcast, and any significant variants in GISAID not broken out by CDC. Five bar-style tree-charts, for fortnights through March 2–15. Legend of last fortnight, organized by subheadings of color-grouped families and convergent clusters. Percentages overlay each color key, reflecting share as of most recent tree-chart. Essentially all WHO-Vaccine-Target JN.1. JN.1.11 accounts for over three fifths; JN.1.11 + FLiRT for near half. For fortnight of 1/19–2/1, packed bubble charts fill single-variant tiles, indicating diversification of those variants (per GISAID) that wouldn't otherwise be apparent from CDC's Nowcast. Legend: LP.8.1 [purple]: 47% - LP.8.1.1 / NY† & other LP.8.1 JN.1 + FLiRT-KS [browns]: 26% - XEC.2†, XEC.8† & other XEC 2% - XEC.4 2% - XEQ ⅒% - other KS.1 JN.1.11 [greens]: ¾% - KP.3 15% - MC.10.1, MC.28.1, MC.19, MC.1 & other KP.3.1.1 / MC JN.1 + FLiRT [reds]: 4% - LF.7 3% - LB.1.3.1 / NL 0% - LB.1 JN.1.11 + FLiRT [blues]: ½% - XEK 0% - KP.2.3 & KP.1.1.3 / LP Other [greys]: ½% - JN.1.16 ⅐% - other WHO-Vaccine-Target JN.1 ⅒% - Other (not specified) † Dagger variants are not broken out by CDC, yet represent a significant share of recent GISAID sequences.
פומבי
Augie Ray

This week's three-minute update on #COVID19 conditions in the US:

- COVID has declined to low levels nationally
- The South and Midwest are at moderate viral risks
- 14 states are at very high or high viral activity
- Tomorrow is Long COVID Awareness Day, and some pertinent links are provided.

medium.com/@augieray_66704/win

Medium · Winter COVID and Viral Respiratory Season Coming to an End: Update for March 14, 2025מאת Augie Ray
פומבי
Calishat

Good morning, y'all. 5 years ago today I did the first issue of CoronaBuzz, a daily newsletter for updates about covid. Over the next 2.5 years I indexed and tagged over 13,000 articles about covid-19 and its impacts around the world. I am still updating that dataset though much more slowly than I was.

The collection is part of ResearchBuzz Firehose. I have an article on how to explore, search, and monitor it here: researchbuzz.me/2024/03/14/cor . I hope you find it useful.

ResearchBuzz · CoronaBuzz: Navigating an Collection of Over 13,800 Covid-Related Article Summaries
עוד מאת ResearchBuzz
#covid19#coronavirus
פומבי *
Mike Honey

Australian COVID-19 weekly stats update:

The risk estimate is trending gently upwards, now at 0.4% “Currently Infectious”, or 1-in-239.

That implies a 12% chance that someone is infectious in a group of 30.

Waves driven by the new LP.8.1.* variant have shown relatively low peaks in most places, and it is showing slow growth in the Australian genomic sequencing data.
aus.social/@mike_honey_/114135

#COVID19 #Australia @auscovid19
🧵

פומבי
Autonomie und Solidarität

Eine Ökonomie des Krieges

Ein spannender Text aus Italien aus dem Jahr 2024 zur Polykrise und wie bestimmte Entwicklungen seit der Corona-Pandemie in die Militarisierung von Staaten und Transformationen zur Kriegswirtschaft übergegangen sind.

xn--untergrund-blttle-2qb.ch/p

'Kasernenausdrücke wie „Wir sind an der Front“ oder „Hommage an die Kriegshelden“ wurden endlos wiederholt, ebenso wie die Wiederkehr veralteter patriotischer Rhetorik und Nationalhymnen auf Balkonen, die angesichts der prekären Gesundheitssituation ebenfalls nur von kurzer Dauer waren. Die menschenleeren Strassen erweckten den Eindruck einer Ausgangssperre, die bis zu einem gewissen Grad die wissenschaftlichen Erkenntnisse über die Entwicklung der Pandemie und die möglichen Lösungen zur Vorbeugung und Behandlung verdunkelte. Diese Massnahmen wurden in einen Rahmen gestellt, der an die Simulation einer Kriegssituation erinnerte. 

Leopard 2A6M CAN der Canadian Army (rechts) auf der Rüstungsmesse Eurosatory.
Untergrund-BlättleEine Ökonomie des Krieges: Das Kind der permanenten wirtschaftlichen DepressionDer Trend zur Kriegswirtschaft hat sich seit der Pandemie Covid 19 herausgebildet. Was auch immer der Ursprung von Covid 19 war, der schockierendste Aspekt war die Kriegssprache, die sofort in den Medien des Regimes die Runde machte.
#Corona#Covid#Pandemie
תגובה לשרשור
פומבי
tj (i make it past the end)

"The act of forgetting has always been a tool of oppression. We cannot adequately resist that which has been revised, erased, or forgotten by our community members. But few will acknowledge that this is happening with COVID. Just as one may utter that “slavery was back then, get over it”, when we use verbiage like “post-pandemic” we are rendering oppression as a static past event rather than an ever-evolving present that shapes our shared future. This tactic has always been useful to those who wish to profit off of our suffering and the cycle will continue to repeat if we do not acknowledge and act on the truth of our current reality. If we do not reckon with our failures to each other around COVID and do the work to remedy it, are we better than those who try to ban our people’s histories’ from the schools? We aid in the crusade to forget every day when we do not consider the pandemic as both current and deadly."

~V. Copeland

forgeorganizing.org/article/re

The ForgeReflecting on COVID, Year 5 - The ForgeVee Copeland, a disabled organizer and former policy analyst details their experience facing the lack of care in movement strategy around surviving the current administration It has been a treacherous five years since the COVID pandemic began.  According to the World Health Organization, more than seven million people across the globe have died from COVID-19, […]
#Covid#CovidIsntOver#CovidIsAirborne
פומבי
aby is tired of your bullshit

“If we were to see immune damage manifesting at a population level, it would look like what we’re seeing today: big waves of common illnesses. Unusual spikes of uncommon illnesses. Course reversal for previously declining and eliminated illnesses. An unexplained, global wave of sickness.”

thegauntlet.news/p/kids-keep-g

The Gauntlet · Kids keep getting sicker as evidence for COVID immune damage buildsמאת Julia Doubleday
#covid#covid19#GetVaccinated
תגובה לשרשור
פומבי *
datum (n=1)

"SARS-CoV-2 spike RNA- and SARS-CoV-2-related inflammation persist in the epipharynx for more than six months post infection. Although no expression of the SARS-CoV-2 spike protein in the epipharynx was evident in these patients with long COVID, genetic analysis revealed activation of [...] the SARS-CoV-2 signalling pathway in epithelial cells, B cells, and pDCs. This aligns with theories that even nonactive viral fragments may possess biological significance. This persistence of inflammation, identified for the first time at the genetic level, highlights the epipharynx as a critical site for continual immune responses in long COVID patients, suggesting that residual viral antigens may contribute to the chronic symptoms experienced"

"After the administration of EAT [epipharyngeal abrasive therapy] once a week for 3 months, the expression of viral RNA disappeared in patients 1 and 2. Patient 3 presented a substantial reduction in viral RNA expression; although complete clearance was not achieved, a marked decrease was observed."

"observed dysregulation of immune and ciliary pathways" - might explain the chronic nonsmoker cough that seems more common now

"These findings suggest that T cells still play a subtle role in the immune dysregulation observed in patients with long COVID. Collectively, these findings indicate that interactions among pDCs, B cells, plasma cells, and T cells contribute to the chronic inflammation and immune dysregulation characteristic of patients with long COVID"

"In the pre-EAT state of long COVID Patient 2, the tissue surface was predominantly covered by ciliated epithelium (Cluster 7). In contrast, following treatment, the ciliated epithelium was no longer observed, and a new cluster of squamous epithelial cells (Cluster 12) emerged"

"EAT effectively eliminates the inflamed ciliated epithelium in patients with long COVID and induces the formation of squamous cells with high barrier function"

nature.com/articles/s41598-025

thanks @MEActNOW

NatureSpatial transcriptomics of the epipharynx in long COVID identifies SARS-CoV-2 signalling pathways and the therapeutic potential of epipharyngeal abrasive therapy - Scientific ReportsIn this study, the critical role of the epipharynx in managing long-term coronavirus disease 2019 (COVID-19), and in particular, how residual SARS-CoV-2 RNA affects signalling pathways in the epipharynx were investigated via spatial gene expression analysis (Visium HD). Moreover, we hypothesize that epipharyngeal abrasive therapy (EAT) targeting the epipharynx could improve long COVID symptoms by modulating local inflammation and gene expression. We conducted a comparative analysis of the gene expression profiles of three patients with long COVID and two control individuals without COVID-19. Residual SARS-CoV-2 RNA was detected in the epipharynx of patients with long COVID, along with the activation of signalling pathways in epithelial and immune cells. After EAT, the viral RNA was either completely cleared or significantly reduced. T-cell receptor signalling pathways were suppressed; the levels of proinflammatory cytokines, such as interleukin-6 and tumour necrosis factor-α, were reduced; and excessive antibody production was mitigated. Histology showed that EAT effectively eliminated the inflamed, dysfunctional ciliated epithelium. This study clarifies that SARS-CoV-2 has long-term effects on the immune response in the epipharynx, emphasizing the need to focus on chronic epipharyngitis as a potential cause of long COVID. Furthermore, EAT may offer a promising approach to alleviating persistent long COVID symptoms.
#COVID#COVID19#SARSCoV2
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